Results 121 to 130 of about 1,161,238 (398)

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

The role of subjective, interpersonal, and structural social isolation in 12-month and lifetime anxiety disorders

BMC Public Health
Background Anxiety disorders are among the most prevalent psychiatric conditions worldwide, and the incidence of anxiety disorders among adults in the U.S. have increased over the last decade.
Ann W. Nguyen, Harry Owen Taylor, Robert Joseph Taylor, Alexis Z. Ambroise, Tyrone Hamler, Weidi Qin, Linda M. Chatters   +6 more
doaj   +1 more source

Patterns of situational appraisal in experiences of worry and anxiety [PDF]

, 2001
Three studies investigating differences in people's appraisals of worry and anxiety situations are presented. First, data from a study by Reisenzein & Spielhofer (1994) were reanalyzed. Second, two further studies were conducted to replicate the findings
Muijs, Marion, Stoeber, Joachim
core   +1 more source

Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain

Advanced Science, EarlyView.
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang, Xiuru Ji, Yu Sun, Han Wang, Ting Wang, Tao Luo, Yanyong Cheng, Jia Yan, Dalong Ni, Hong Jiang   +9 more
wiley   +1 more source

Is the beck anxiety inventory a good tool to assess the severity of anxiety? A primary care study in The Netherlands study of depression and anxiety (NESDA)

BMC Family Practice, 2011
Background Appropriate management of anxiety disorders in primary care requires clinical assessment and monitoring of the severity of the anxiety. This study focuses on the Beck Anxiety Inventory (BAI) as a severity indicator for anxiety in primary care ...
van der Feltz-Cornelis Christina M, Muntingh Anna DT, van Marwijk Harm WJ, Spinhoven Philip, Penninx Brenda WJH, van Balkom Anton JLM   +5 more
doaj   +1 more source

COMORBID ANXIETY IN PATIENTS WITH PSYCHOSIS [PDF]

, 2009
A diagnosis of psychosis has tended to discount the considerable degree of emotional disorder associated with it, in a manner that may also inform psychological treatment options. Depression and anxiety are often associated with schizophrenia.
Lilijana Šprah, Mojca Zvezdana Dernovšek   +1 more
core   +1 more source

Cognitive behaviour therapy versus counselling intervention for anxiety in young people with high-functioning autism spectrum disorders: a pilot randomised controlled trial [PDF]

, 2017
The use of cognitive-behavioural therapy (CBT) as a treatment for children and adolescents with autism spectrum disorder (ASD) has been explored in a number of trials.
AC James, BA McArthur, BD McLeod, C Barrowclough, C Lord, CJ Morrell, CK Conners, CK Higa-McMillan, D Ung, D Ung, Dee A. Press, DG Sukhodolsky, DG Sukhodolsky, E Godfrey, EA Storch, F Steensel Van, Hadi Shaker-Naeeni, Hilary Gahan, I Gibbard, J Cape, J Cohen, JJ Wood, JM Liber, JN Constantino, JR Landis, KW Fjermestad, Laura Reynolds, Louisa Donald, Louise Scrivener, M King, M Lerner, M Rutter, M Sung, Mahesh Kulkarni, P Bower, R Brown, R Loomes, R Rosenthal, RA Vasa, S Reynolds, Susan W. White, Suzanne M. Murphy, SW White, Uttom Chowdhury, V Hallett, WK Silverman, WR Andrews, Zeinab Iqbal   +47 more
core   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

A Lifetime Prevalence of Comorbidity Between Bipolar Affective Disorder and Anxiety Disorders: A Meta-analysis of 52 Interview-based Studies of Psychiatric Population

EBioMedicine, 2015
Background: Bipolar affective disorder has a high rate of comorbidity with a multitude of psychiatric disorders and medical conditions. Among all the potential comorbidities, co-existing anxiety disorders stand out due to their high prevalence.
Behrouz Nabavi, Alex J. Mitchell, David Nutt   +2 more
doaj   +1 more source

A contextual approach to experiential avoidance and social anxiety: evidence from an experimental interaction and daily interactions of people with social anxiety disorder.

Emotion, 2014
Experiential avoidance (EA), the tendency to avoid internal, unwanted thoughts and feelings, is hypothesized to be a risk factor for social anxiety. Existing studies of experiential avoidance rely on trait measures with minimal contextual consideration ...
T. Kashdan, Fallon R. Goodman, Kyla A. Machell, Evan M. Kleiman, Samuel S. Monfort, J. Ciarrochi, J. Nezlek   +6 more
semanticscholar   +1 more source