Results 121 to 130 of about 553,674 (309)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Debt Counseling: The Challenges of Implementation Directive (EU) 2023/2225 within the Romanian Social Services Landscape

open access: yesTransylvanian Review of Administrative Sciences
This article examines the emerging role of debt counseling within Romania’s social services in the context of Directive (EU) 2023/2225. Over-indebt­edness is increasingly recognized across Europe as both an economic and a social risk, with significant ...
Rodica Diana Apan   +1 more
doaj   +1 more source

Social assistance programme impacts on women's and children's diets and nutritional status. [PDF]

open access: yesMatern Child Nutr, 2022
Olney DK   +5 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Down but Not Out: Reforming Social Assistance Rules that Punish the Poor for Saving [PDF]

open access: yes
Reform is required for social program rules that prevent the poor from saving in Registered Retirement Savings Plans (RRSPs) and Tax Free Savings Accounts (TFSAs), according to this study.
John Stapleton
core  

Social assistance in the Netherlands [PDF]

open access: yes, 2018
This contribution introduces the Dutch system of social assistance, its background and functioning, and current ...
Cremers, Jan; id_orcid, Cremers, Jan
core  

Social Registries for Social Assistance and Beyond

open access: yes, 2017
This paper makes several contributions. First, it presents a ‘guidance note’ on the framework for Social Registries, anchoring the definition of these systems in their functions along the Delivery Chain and their social policy role as inclusion systems, while clarifying terminology in a manner that is consistent with IT standards in the discussion of ...
Leite, Phillippe   +4 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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