Results 71 to 80 of about 1,091,145 (261)

News Stance Discrimination Based on a Heterogeneous Network of Social Background Information Fusion. [PDF]

Entropy (Basel), 2022
Ren Y, Liu Y, Chen J, Guo X, Shi J, Jia M.   +5 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Effect of the ethnic, profession, gender, and social background on the perception of upper dental midline deviations in smile esthetics by Chinese and Black raters. [PDF]

BMC Oral Health, 2023
Musa M, Awad R, Mohammed A, Abdallah H, Elhoumed M, Al-Waraf L, Qu W, Alhashimi N, Chen X, Wang S.   +9 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts. [PDF]

Sci Rep, 2022
Silventoinen K, Piirtola M, Jelenkovic A, Sund R, Tarnoki AD, Tarnoki DL, Medda E, Nisticò L, Toccaceli V, Honda C, Inui F, Tomizawa R, Watanabe M, Sakai N, Gatz M, Butler DA, Lee J, Lee SJ, Sung J, Franz CE, Kremen WS, Lyons MJ, Derom CA, Vlietinck RF, Loos RJF, Tynelius P, Rasmussen F, Martin NG, Medland SE, Montgomery GW, Brandt I, Nilsen TS, Harris JR, Tyler J, Hopper JL, Magnusson PKE, Pedersen NL, Dahl Aslan AK, Ordoñana JR, Sánchez-Romera JF, Colodro-Conde L, Rebato E, Zhang D, Pang Z, Tan Q, Silberg JL, Maes HH, Boomsma DI, Sørensen TIA, Korhonen T, Kaprio J.   +50 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

A MORAL BUDGET FROM A MORAL MOVEMENT: The Poor People’s Campaign

Sur: International Journal on Human Rights, 2019
The Poor People’s Campaign: A National Call for Moral Revival is a national campaign in the U.S. that has grown to more than 40 states across the country. Taking up the legacy of Rev. Dr.
Shailly Gupta Barnes
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

[Associations between students' social background, mode of instruction and learning outcomes during the pandemic]. [PDF]

Z Bild Forsch, 2022
Obermeier R, Lenz S, Helm C.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source