Results 91 to 100 of about 16,009,179 (311)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Challenges and opportunities in coding the commons: problems, procedures, and potential solutions in large-N comparative case studies

International Journal of the Commons, 2016
On-going efforts to understand the dynamics of coupled social-ecological (or more broadly, coupled infrastructure) systems and common pool resources have led to the generation of numerous datasets based on a large number of case studies.
Elicia Ratajczyk, Ute Brady, Jacopo A. Baggio, Allain J. Barnett, Irene Perez-Ibarra, Nathan Rollins, Cathy Rubiños, Hoon C. Shin, David J. Yu, Rimjhim Aggarwal, John M. Anderies, Marco A. Janssen   +11 more
doaj   +1 more source

Temporal lobe epilepsy and social behavior: An animal model

, 2008
Social behavior depends on the integrity of social brain circuitry. The temporal lobe is an important part of the social brain, and manifests morphological and functional alterations in autism spectrum disorders (ASD).
COLUGNATI, Diego B., Marin, Joao Carlos M. [UNIFESP], CYSNEIROS, Roberta M., XAVIER, Gilberto F., ZILBOVICIUS, Monica, MERCADANTE, Marcos T., MOURA, Paula J., MARIN, Joao Carlos M., Colugnati, Diego Basile [UNIFESP], CAVALHEIRO, Esper A., Mercadante, Marcos T. [UNIFESP], SCORZA, Fulvio A.   +11 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The Influence of Mating Context on Creativity: Insights from Simulated Dating Scenarios

Evolutionary Psychology
Creativity offers both survival and reproductive benefits, being a desirable trait in potential mates and linked to fertility and sexuality. We investigated whether viewing attractive faces of potential short-term or long-term partners in a simulated ...
Katarzyna Galasinska, Aleksandra Szymkow, Marco Antonio Correa Varella   +2 more
doaj   +1 more source

Missing values in peer assessment of social behavior using the RCP

, 2001
This article deals with probable causes for missing values when using the Revised Class Play instrument for peer assessment of social behavior. The study was conducted with 10-13 year old primary school children in Sweden.
Vedder, Paul, Lund University., O'Dowd, Mina,   +2 more
core  

Interpretation and Production of Interpersonal Behavior [PDF]

, 2002
The question of how people interpret (decode) and construct (encode) the meaning of social behavior is central to the understanding of social interaction.
Morris, Catherine
core  

Active and Passive Social Media Use and Symptoms of Anxiety and Depressed Mood Among Icelandic Adolescents [PDF]

, 2019
Adolescent use of social media platforms such as Facebook, Instagram, and Snapchat has increased dramatically over the last decade and now pervades their everyday social lives.
Sigurvinsdottir, Rannveig, Allegrante, John P., Thorisdottir, Ingibjorg, Asgeirsdottir, Bryndis Bjork, Sigfusdottir, Inga Dora, Sigfusdottir, Inga, Thorisdottir, Ingibjorg E.   +6 more
core   +1 more source