Results 131 to 140 of about 16,009,179 (311)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Adaptation and psychometric evaluation of the breastfeeding self-efficacy scale to assess exclusive breastfeeding: a cross-sectional study in rural China

BMC Pregnancy and Childbirth
Background Despite the benefits of exclusive breastfeeding, the proportion of exclusively breastfed children remains low in rural China. Self-efficacy is one of the most crucial modifiable factors predicting breastfeeding behavior.
Linhua Li, Zhengjie Cai, Xinru Zhou, Jieyuan Feng, Chang Sun, Yuju Wu, Scott Rozelle, Huan Zhou   +7 more
doaj   +1 more source

From use to abuse: psychological, neurobiological, and spiritual pathways in relational harm and recovery

Frontiers in Behavioral Neuroscience
This viewpoint examines the distinction between relational “use” and “abuse” through psychological, neurobiological, relational, and spiritual lenses. It conceptualizes use as a form of mutual and ethical interdependence, whereas abuse is understood as a
Shilpa Bhardwaj, Arif Ali, Fayaz Ahmad Paul   +2 more
doaj   +1 more source

How should behavior analysis interact effectively with the social sciences [PDF]

, 2006
: I would like to discuss some perspectives on scientific approaches traditionally viewed as mutually incompatible or antagonistic. This might be illustrated by e.g.
Sandaker, Ingunn
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Local policy governance arrangements and COVID-19-related mortality in municipalities in Japan: a cross-sectional ecological study

Frontiers in Public Health
IntroductionCOVID-19-related mortality varied substantially within and across countries, which may not be fully explained by demographic and clinical differences.
Yuki Nakamoto, Hideki Hashimoto
doaj   +1 more source

Co-evolution of Social Networks and Behavior in Social Dilemmas: Theoretical and Empirical Perspectives [PDF]

, 2009
Social networks play an important role in explanations of outcomes of social dilemmas; situations in which goal-directed individual action can lead to a collectively suboptimal outcome.
Solidarity 2000+ (ICS), Afd sociologie, Social Networks, Solidarity and Inequality, Theoretical Micro-Economics, Corten, R.   +4 more
core   +1 more source

Los Angeles County Social Survey, 1993 (LACSS)

, 1993
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source