Results 151 to 160 of about 1,116,296 (262)

Circulating extracellular vesicle microRNAs mediate immune modulation of social behavior in male mice. [PDF]

Nat Commun
Matoba K, Dohi E, Garcia PA, Francis-Oliveira J, Mirramezanializamini M, Berkiks I, Anguiano F, Badrani JH, Fatoba O, Choi EY, See J, Parvez MSA, Kochi T, Ito N, Mitani R, Rose IVL, Imai T, Crossman DK, Pletnikov MV, Witwer KW, Niwa M, Kano SI.   +21 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Involvement of CB1 cannabinoid receptors in methamphetamine-related decision-making and social behavior deficits. [PDF]

BMC Neurosci
Mousavi T, Hatami N, Niknamfar S, Naseri M, Rafaiee R, Tamijani SMS, Ranaiy MS, Ghazvini H.   +7 more
europepmc   +1 more source

Copper deficiency impairs oligodendrocyte maturation and social behavior via mitophagy and mTOR suppression in ASD. [PDF]

Sci Adv
Usui N, Doi M, Berto S, Matsuoka K, Ishida R, Miyauchi H, Fujiwara Y, Irie K, Toritsuka M, Yamauchi T, Hirai T, Xie MJ, Kayashima Y, Umeda N, Iwata K, Okumura K, Harada T, Katayama T, Tsujii M, Matsuzaki H, Makinodan M, Shimada S.   +21 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Mining exceptional social behavior on attributed interaction networks. [PDF]

Mach Learn
Atzmueller M, Centeio Jorge C, Rebelo de Sá C, Heravi BM, Gibson JL, Rossetti RJF.   +5 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Understanding Bystander's Response and Intentions in Non-Consensual Sexting: Insights from the Theory of Normative Social Behavior. [PDF]

Arch Sex Behav
Villa-Henao D, Ojeda M, Muñoz-Fernández N, Del Rey R, Mora-Merchán JA.   +4 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

COVID-19 pandemic changes in social behavior relevant for transmission of Mycobacterium tuberculosis. [PDF]

BMC Res Notes
Nelson KN, Harton P, Cohen T, Willis F, Yoshii H, Naidoo K, Lutchminarain K, Campbell A, Omar SV, Auld SC, Brust JCM, Gandhi NR, Shah NS.   +12 more
europepmc   +1 more source