Results 121 to 130 of about 3,983,391 (348)

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Social Contribution and Optimal Level of Road Capital in South Korea

, 2013
Kook Woo-Kag
openalex   +1 more source

Social Capital and Development. [PDF]

, 2004
The purpose of this paper is to reflect, from an economist's point of view, on the methodological issues raised by the study of social capital. This term has been used in many different ways to cover a broad range of phenomena (Durlauf & Fafchamps 2002). Perhaps it is best seen as a way of federating research programs in various social sciences, If
openaire   +2 more sources

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

Advanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang, Jingxuan Wang, Kerong Tu, Xiaobing Huang, Liangliang Lv, Mingjie Peng, Qiqi Xu, Hongmei Liu, Qiang Sun, Lulu Cai   +9 more
wiley   +1 more source

Capital Social y Capital [PDF]

Polis (Santiago), 2011
Bolívar Espinoza, Gardy Augusto, Elizalde Hevia, Antonio   +1 more
openaire   +2 more sources

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

Regional Media – Social Capital – Security

Zarządzanie Mediami
Security, in the broadest sense of the word, requires enormous financial expenditure. Equally important, however, is the provision of social capital, garnered through the relationships and connections
Juliusz Braun
doaj   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

The impact of human capital and social capital on entrepreneurship entry: the threshold of human capital-social capital coupling

Humanities & Social Sciences Communications
Human capital and social capital are crucial in shaping entrepreneurial decisions, yet their combined effects on entrepreneurship entry remain insufficiently explored.
Yanyan Sheng, Chenlu Ye, Yiping Sun, Diederich Bakker   +3 more
doaj   +1 more source

A reestruturação dos serviços de saúde no contexto hospitalar e os desafios para o Serviço Social frente à crise sociossanitária e estrutural do capital

, 2023
Rafaela Cabral Farias
openalex   +1 more source