Results 41 to 50 of about 452,232 (264)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Quarantine measures for coronavirus disease 2019 on a cruise ship, Taiwan, February 2020

International Journal of Infectious Diseases, 2020
To early detect coronavirus disease 2019 on an international cruise ship and prevent its spread, Taiwan’s Central Epidemic Command Center implemented on-board quarantine measures on a cruise ship docked at the Port of Keelung, Taiwan, on February 8, 2020.
Yung-Ching Lin, Meng-Yu Chen, Ming-Ching Liu, Yu-Ju Lin, Yu-Hsuan Lin, Jiun-Shian Kuo, Pi-Sheng Wang, Chung-Liang Shih   +7 more
doaj   +1 more source

Sociodemographic Factors Associated with COVID-19 Vaccination among People in Guatemalan Municipalities

Vaccines, 2023
The Republic of Guatemala’s reported COVID-19 vaccination coverage is among the lowest in the Americas and there are limited studies describing the disparities in vaccine uptake within the country. We performed a cross-sectional ecological analysis using
Rewa Choudhary, Emily Carter, Jose Monzon, Allison Stewart, Jennifer Slotnick, Leslie L. Samayoa Jerez, David S. Rodriguez Araujo, Emily Zielinski-Gutierrez, Parminder S. Suchdev   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Comparison of several survey-based algorithms to ascertain type 1 diabetes among US adults with self-reported diabetes

BMJ Open Diabetes Research & Care, 2020
Introduction Defining type of diabetes using survey data is challenging, although important, for determining national estimates of diabetes. The purpose of this study was to compare the percentage and characteristics of US adults classified as having ...
Sarah S Casagrande, Catherine C Cowie, Linda S Geiss, Kai McKeever Bullard, Giuseppina Imperatore, Sharon H Saydah, Sarah E Lessem, Trevor J Orchard, Andy Menke, Keith F Rust   +9 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The role of the environment: how mask wearing varies across different activities

BMC Public Health
Background People’s decisions to engage in protective health behaviors, such as mask wearing during the COVID-19 pandemic, are influenced by environmental and social contexts.
Ciara Nestor, Giulia Earle-Richardson, Christine E Prue   +2 more
doaj   +1 more source

Association between menthol cigarette smoking and current use of electronic cigarettes among us adolescents.

Tobacco Prevention and Cessation, 2017
Introduction Some e-cigarette manufacturers have marketed e-cigarette flavors branded after popular menthol cigarette brands, such as Newport. Such targeted marketing has the potential to increase the likelihood of e-cigarette initiation among menthol ...
Israel Agaku
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source