Health and Disease and the Changing Social and Cultural Environment of Man
Edward Stainbrook
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Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Visualizing DEPICT: A Multistep Model for Participatory Analysis in Photovoice Research for Social Change. [PDF]
Switzer S, Flicker S.
europepmc +1 more source
Intergroup Contact and Social Change
N. K. Reimer+9 more
semanticscholar +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
Gamo's cultural forum-Dubussha as a tool for social change communication: Illiteracy and child labor abuse as a case in point. [PDF]
Ayalew MT, Walea Wanke T.
europepmc +1 more source
Intercultural discussion of conceptual universals in discourse: joint online methodology to bring about social change through novel conceptualizations of Covid-19. [PDF]
Schnell Z, Ervas F.
europepmc +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
Medical Students and Issues of Social Change: Gender Inclusion in Student Organizations. [PDF]
James E, Salahou A.
europepmc +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee+9 more
wiley +1 more source