Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Dissonance as a productive force in the emergence of alternative crisis support and impetus for social change-principles and organizational form of the association Open Dialogue Leipzig e.V. [PDF]
Klatt T +5 more
europepmc +1 more source
The Coevolution of Social Learning and Sensitivity to Changing Environments [PDF]
Richard McElreath
openalex +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Leading a Healthcare Organization During a Period of Social Change: A Qualitative Study of Chief Executive Officers. [PDF]
Meltzer KK +4 more
europepmc +1 more source
In Service of the Society? Medical Associations as Agents of Social Change-Implications for Health Policy and Education in Israel. [PDF]
Levi B, Davidovitch N, Dopelt K.
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Support for Social Change Among Members of Advantaged Groups: The Role of a Dual Identity Representation and Accepting Intergroup Contact. [PDF]
Frisch LK +6 more
europepmc +1 more source
The Influence of the Specification of Climate Change Damages on the Social Cost of Carbon [PDF]
Robert E. Kopp +3 more
openalex +1 more source

