Results 211 to 220 of about 27,162,291 (391)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Believing that social change is possible: Collective efficacy to promote engagement and mobilization of non-Roma as allies. [PDF]

Br J Soc Psychol
Urbiola A, López-Rodríguez L, Torres-Vega LC, Poslon XD, Lášticová B, Pántya J, Szekeres H, Kende A.   +7 more
europepmc   +1 more source

The effects of facebook use on network social capital and subjective well-being: A generational cohort analysis from the Taiwan social change survey. [PDF]

Heliyon, 2023
Wu MS.
europepmc   +1 more source

Artists and Social Change [PDF]

, 2009
Carter, Curtis
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

From who we are to what we are willing to do for social change: The action-bound role of efficacy perceptions. [PDF]

Br J Soc Psychol
Lucarini A, Cocco VM, Vezzali L, Mannarini T, Çakal H.   +4 more
europepmc   +1 more source

Does believing in different types of religion affect subjective wellbeing? Analysis of the public data of the Taiwan Social Change Survey. [PDF]

Front Psychol, 2022
Ding Y, Huo W, Jin Y.
europepmc   +1 more source

CLIMATE CHANGE AND THE MARGINALIZED: EXPLORING THE ROLE OF SOCIAL WORK IN PROTECTING VULNERABLE POPULATIONS IN BALOCHISTAN

Hafsa Karim, Dr. Abdul Rahim Changezi
openalex   +1 more source

Handbook of Communication for Development and Social Change

, 2019
R. Colle
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source