Results 91 to 100 of about 537,885 (259)

Amartya Sen e a escolha social: uma extensão da teoria da justiça de John Rawls? Amartya Sen and the social choice: is it an extension of John Rawls's theory of justice?

Revista de Economia Contemporânea, 2012
O objetivo é apresentar a visão de Amartya Sen quanto à possibilidade da escolha social como um exercício comparativo e reflexivo com indivíduos comprometidos, tendo como ponto de partida a justiça como equidade de John Rawls.
Solange Regina Marin, André Marzulo Quintana   +1 more
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Work as a social determinant of maternal health: A qualitative exploration of college-educated Black women’s experiences at work during pregnancy and postpartum

Women's Health
Background: Black women are disproportionately impacted by higher rates of maternal mortality in the United States (US). Limited research has focused on adverse maternal health outcomes among college-educated Black women, although research has found ...
Serwaa S Omowale, Laurenia C Mangum, Andrea Joseph-McCatty, Cherell Cottrell-Daniels, Kaiya A Farris, Rashon King, Brittany C Slatton   +6 more
doaj   +1 more source

Using social choice theory and acceptability analysis to measure the value of health systems. [PDF]

PLoS One, 2020
Shen H, Sui Y, Fu Y.
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Understanding and using experiences of social care to guide service improvements: translating a co-design approach from health to social care

Health and Social Care Delivery Research
Background Local authorities need to find new ways of collecting and using data on social care users’ experiences to improve service design and quality.
Sara Ryan, Jane Maddison, Kate Baxter, Mark Wilberforce, Yvonne Birks, Emmie Morrissey, Angela Martin, Ahmed Lambat, Pam Bebbington, Sue Ziebland, Louise Robson, Louise Locock   +11 more
doaj   +1 more source

The Asymmetry of population ethics: experimental social choice and dual-process moral reasoning. [PDF]

Econ Philos, 2020
Spears D.
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source