Results 111 to 120 of about 13,018,390 (251)

Preference of Social Choice in Mathematical Economics [PDF]

open access: yes
Mathematical Economics is closely related with Social Choice Theory. In this paper, an attempt has been made to show this relation by introducing utility functions, preference relations and Arrow’s impossibility theorem with easier mathematical ...
Haradhan Kumar Mohajan   +2 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Understanding and using experiences of social care to guide service improvements: translating a co-design approach from health to social care

open access: yesHealth and Social Care Delivery Research
Background Local authorities need to find new ways of collecting and using data on social care users’ experiences to improve service design and quality.
Sara Ryan   +11 more
doaj   +1 more source

A Public Choice Analysis of Digital Content Protection Policy: The Paradox of Technological Protection and Digital Regulation

open access: yes
This paper analyzes digital content protection policy from a public choice perspective. It examines how legal protection and public enforcement for digital content are determined.
Youngshin Kim   +1 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Modularity and Optimality in Social Choice [PDF]

open access: yes
Marengo and the second author have developed in the last years a geometric model of social choice when this takes place among bundles of interdependent elements, showing that by bundling and unbundling the same set of constituent elements an authority ...
Simona Settepanella, Gennaro Amendola
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Implementation of Social Choice Functions via Demanding Equilibria [PDF]

open access: yes
We consider agents who do not have any information about others' preferences. In this situation they attempt to behave such as to maximize their chances to obtain their most preferred alternative.
Vincent Merlin, Jörg Naeve
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Improving support and planning ahead for older people with learning disabilities and family carers: a mixed-methods study

open access: yesHealth and Social Care Delivery Research
Background People with learning disabilities are living longer. Despite government policy to encourage people to lead supported lives in their community, family carers often maintain support due to dissatisfaction with services.
Sara Ryan   +10 more
doaj   +1 more source

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