Results 71 to 80 of about 3,794,400 (241)

School Assignment, School Choice and Social Mobility [PDF]

open access: yes
We estimate the chances of poor and non-poor children getting places in good schools, analysing the relationship between poverty, location and school assignment. Our dataset allows us to measure location and distance very precisely.
Adam Briggs, Simon Burgess
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Michael Dummett on social choice and voting [PDF]

open access: yes
Michael Dummett worked on the theoretical aspects of aggregation of individual preferences and on the strategic aspects of voting theory. He also extended Black’s analysis of single-peaked preferences for majority rule to the case of voting games ...
Maurice Salles
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Borda Measure for Social Choice Functions [PDF]

open access: yes
The question addressed in this paper is the order of magnitude of the difference between the Borda rule and any given social choice function. A social choice function is a mapping that associates a subset of alternatives to any profile of individual ...
Le Breton, Michel, Truchon, Michel
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Social choice among complex objects: Mathematical tools [PDF]

open access: yes
Here the reader can find some basic definitions and notations in order to better understand the model for social choise described by L. Marengo and S. Settepanella in their paper: Social choice among complex objects.
Simona Settepanella
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Discrete Choice with Social Interactions I: Theory [PDF]

open access: yes
This paper provides an analysis of aggregate behavioral outcomes when individual utility exhibits social interaction effects. We study generalized logistic models of individual choice which incorporate terms reflecting the desire of individuals to ...
Steven N. Durlauf, William A. Brock
core  

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