Results 81 to 90 of about 517,196 (309)

Amartya Sen e a escolha social: uma extensão da teoria da justiça de John Rawls? Amartya Sen and the social choice: is it an extension of John Rawls's theory of justice?

Revista de Economia Contemporânea, 2012
O objetivo é apresentar a visão de Amartya Sen quanto à possibilidade da escolha social como um exercício comparativo e reflexivo com indivíduos comprometidos, tendo como ponto de partida a justiça como equidade de John Rawls.
Solange Regina Marin, André Marzulo Quintana   +1 more
doaj  

The Utilitarian Social Choice Functional [PDF]

SSRN Electronic Journal, 2018
Introducimos el concepto de una opción social funcional y proporcionamos dos caracterizaciones axiomáticas de la opción social utilitaria funcional. Posteriormente, consideramos el utilitarismo ponderado de Harsanyi y establecemos dos proposiciones más sobre el mismo.
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Using social choice theory and acceptability analysis to measure the value of health systems. [PDF]

PLoS One, 2020
Shen H, Sui Y, Fu Y.
europepmc   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Work as a social determinant of maternal health: A qualitative exploration of college-educated Black women’s experiences at work during pregnancy and postpartum

Women's Health
Background: Black women are disproportionately impacted by higher rates of maternal mortality in the United States (US). Limited research has focused on adverse maternal health outcomes among college-educated Black women, although research has found ...
Serwaa S Omowale, Laurenia C Mangum, Andrea Joseph-McCatty, Cherell Cottrell-Daniels, Kaiya A Farris, Rashon King, Brittany C Slatton   +6 more
doaj   +1 more source

The Asymmetry of population ethics: experimental social choice and dual-process moral reasoning. [PDF]

Econ Philos, 2020
Spears D.
europepmc   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Understanding and using experiences of social care to guide service improvements: translating a co-design approach from health to social care

Health and Social Care Delivery Research
Background Local authorities need to find new ways of collecting and using data on social care users’ experiences to improve service design and quality.
Sara Ryan, Jane Maddison, Kate Baxter, Mark Wilberforce, Yvonne Birks, Emmie Morrissey, Angela Martin, Ahmed Lambat, Pam Bebbington, Sue Ziebland, Louise Robson, Louise Locock   +11 more
doaj   +1 more source