Results 101 to 110 of about 14,394,948 (360)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Status Consistency / Inconsistency of the Status Position of Social Classes

Соціологічні студії, 2018
In this article author explains the class inequality in west and east European societies. Also we compare class differences of EU and NEE countries. Summarized evaluation of aggregate social status in the context of the study of social stratification ...
O. M, Kuzmuk
doaj  

Naomi the Poet and Nella the Housewife: Finding a Space to Write from

Miranda: Revue Pluridisciplinaire du Monde Anglophone, 2010
Northern housewife Nella Last and novelist and essayist Naomi Mitchison were from widely different social and cultural backgrounds but shared one common point: both kept wartime diaries for Mass-Observation from 1939 to 1945.
Karen Meschia
doaj   +1 more source

Social Class and Wellbeing among Staff and Students in Higher Education Settings: Mapping the Problem and Exploring Underlying Mechanisms

, 2021
Isla Dougall, Mario Weick, Milica Vasiljevic   +2 more
openalex   +1 more source

The difference that tenure makes [PDF]

, 1991
This paper argues that housing tenures cannot be reduced to either production relations or consumption relations. Instead, they need to be understood as modes of housing distribution, and as having complex and dynamic relations with social classes ...
Andrew Knowles, Bagguley P., Bassett K., Batstone E., Beynon H., Bottomore T., Bradley H., Braverman M., Buck N., Byrne D., Byrne D., Carpenter M., Coates D., Cockbum C., Cooke P., Cousins C., Dahrendorf R., Daunton M. J., de Vroey M., Department of the Environment, Dickens P., Donnison D., Dunleavy P., Ehrenreich B., Forrest R., Forrest R., Gamarnikow E., Goldthorpe J. H., Gordon D. M., Gorz A., Gray F., Hamnett C., Harloe M., Harloe M., Harloe M., Henderson J., Johnson T., Kam V., Kemeny J., Knowles A., Littler C. R., Malpass P., Malpass P., Marshall G., Meegan R., Morris J., Murie A, Murie A., Murie A., Nichols T., Pahl R., Parry N. C. A., Parry N. C. A., Peter Somerville, Pringle R., Rae D. W., Robinson R., Saunders P., Saunders P., Saunders P., Somerville P., Somerville P., Somerville P., Somerville P., Stedman Jones G., Thrift N., Urry J., Willmott P., Wright E. O.   +68 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

The Influence of Gender, Social Class and National Background on Education and Work Career?

Nordic Journal of Migration Research, 2013
In this Swedish study, the combined effects of gender, social and national background on transition within the school system and into the labour market are examined.
Caroline Berggren
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Do Meio à Classe Média: como a “nova classe média” e a “classe média tradicional” percebem sua posição social?

Ciências Sociais Unisinos, 2015
The paper aims to bring new elements to the current debate about the middle class in Brazil, taking the class identities and perceptions about middle class as its object.
André Salata, Celi Scalon
doaj