Results 111 to 120 of about 15,287,714 (336)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Do Meio à Classe Média: como a “nova classe média” e a “classe média tradicional” percebem sua posição social?

Ciências Sociais Unisinos, 2015
The paper aims to bring new elements to the current debate about the middle class in Brazil, taking the class identities and perceptions about middle class as its object.
André Salata, Celi Scalon
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Access to Childcare and Home Care Services across Europe. An Analysis of the European Union Statistics on Income and Living Conditions (EU SILC), 2016. Social Inclusion Report No 8. September 2019 [PDF]

, 2019
This report uses EU-SILC data for 2016 to examine differences by social risk group and social class in access to care services – specifically, childcare and home care for people with an illness or disability.
Grotti, Raffaele, Maitre, Bertrand, Privalko, Ivan, Watson, Dorothy   +3 more
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Attitudes toward gender equality in sport among Europeans

Frontiers in Psychology
IntroductionThis study examines the role of societal, interpersonal, and individual factors in explaining Europeans’ attitudes toward gender equality in sport and the role of interactions between gender, age, and social class.MethodsThe empirical ...
Pamela Wicker, George B. Cunningham
doaj   +1 more source

Socioeconomic Inequality and Social Exclusion in Health: A Review

Dhaulagiri Journal of Sociology and Anthropology, 2013
This paper examines the impact of social inequality and social exclusion on health. Social exclusion in health can be explained by socioeconomic inequality in health as socioeconomic position mediates access to resources including health services ...
Chitra Bahadur Budhthoki
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Divided by class: Government perception and political participation in Indonesia and Bangladesh

Frontiers in Political Science
Political participation is a key indicator of democratic quality, yet in many developing countries, it remains unevenly distributed across social classes. While existing studies have explored government performance and political participation separately,
Nurlinah, Muhammad Chaeroel Ansar, Suci Megawati, Kuntala Chowdhury   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source