Results 101 to 110 of about 1,124,770 (344)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Intergroup Reconciliation between Flemings and Walloons: The Predictive Value of Cognitive Style, Authoritarian Ideology, and Intergroup Emotions

open access: yesPsychologica Belgica, 2017
Testifying to the gap in fundamental research on positive intergroup outcomes, we investigated reconciliation attitudes in a non-violent intergroup context (i.e., the linguistic conflict in Belgium). By incorporating both important predictors of negative
Jasper Van Assche   +4 more
doaj   +1 more source

Visual attention in autism families: ‘unaffected’ sibs share atypical frontal activation [PDF]

open access: yes, 2009
Background: In addition to their more clinically evident abnormalities of social cognition, people with autism spectrum conditions (ASC) manifest perturbations of attention and sensory perception which may offer insights into the underlying neural ...
Baron-Cohen, S, Belmonte, MK, Gomot, M
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Sally and… Cozmo? Training theory of mind using a toy robot: a pilot study

open access: yesFrontiers in Psychology
IntroductionChildren with autism spectrum disorder (ASD) often show impairments in Theory of Mind (ToM). This pilot study examined whether a commercially available toy robot (Cozmo) could support false-belief training within an Applied Behavior Analysis (
Davide Ghiglino   +4 more
doaj   +1 more source

What does the amygdala contribute to social cognition? [PDF]

open access: yes, 2010
The amygdala has received intense recent attention from neuroscientists investigating its function at the molecular, cellular, systems, cognitive, and clinical level. It clearly contributes to processing emotionally and socially relevant information, yet
Adolphs, Ralph
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

The impact of action descriptions on attribution of moral responsibility towards robots

open access: yesScientific Reports
In the era of renewed fascination with AI and robotics, one needs to address questions related to their societal impact, particularly in terms of moral responsibility and intentionality.
Ziggy O’Reilly   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Varieties of social cognition [PDF]

open access: yes, 2008
Recent actions. KEYWORDS: implicit social work Influence within cognition, unconsciousness psychology demonstrates is cognition, corroborated that implicit unconscious by strong measures, empirical cognition priming, evidence, plays automaticity, a but ...
David A. Pizarro   +2 more
core   +2 more sources

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