Results 81 to 90 of about 1,124,770 (344)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Manual Grasparatus: A nifty tool for presenting real objects in fMRI research

open access: yesMethodsX, 2019
One of the greatest challenges in functional magnetic resonance imaging (fMRI) research using real objects as stimuli is their timely delivery and (pseudo)randomized presentation.
Agnieszka M. Nowik   +2 more
doaj   +1 more source

Religious Cognition as Social Cognition [PDF]

open access: yes, 2015
In this paper, I examine the relationship between social cognition and religious cognition. Many cognitive theories of religion claim that these two forms are somehow related, but the details are usually left unexplored and insights from theories of ...
Van Eyghen, Hans
core  

Six month durability of targeted cognitive training supplemented with social cognition exercises in schizophrenia. [PDF]

open access: yes, 2020
Background:Deficits in cognition, social cognition, and motivation are significant predictors of poor functional outcomes in schizophrenia. Evidence of durable benefit following social cognitive training is limited.
Biagianti, Bruno   +10 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Social cognition in multiple sclerosis and its subtypes: a protocol for systematic review and meta-analysis [PDF]

open access: gold, 2020
XiaoGuang Lin   +7 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Face Cognition: A Set of Distinct Mental Abilities [PDF]

open access: yes, 2007
Perceiving, learning, and recognizing faces swiftly and accurately is of paramount importance to humans as a social species. Though established functional models of face cognition<sup>1,2</sup> suggest the existence of multiple ...
Grit Herzmann   +3 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Multimodal mobile brain and body imaging for quantification of dance motor sequence learning

open access: yesMethodsX
Understanding motor learning in naturalistic settings presents a key challenge in neuroscience. While paradigms like the Discrete Sequence Production (DSP) task have advanced our knowledge, investigating more naturalistic tasks like dance with multi ...
Russell W. Chan   +5 more
doaj   +1 more source

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