Results 111 to 120 of about 1,105,746 (347)
Enactivism, other minds, and mental disorders [PDF]
, 2019 Although enactive approaches to cognition vary in terms of their character and scope, all endorse several core claims. The first is that cognition is tied to action.
Krueger, Joel
core +2 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
The impact of action descriptions on attribution of moral responsibility towards robots
Scientific ReportsIn the era of renewed fascination with AI and robotics, one needs to address questions related to their societal impact, particularly in terms of moral responsibility and intentionality.
Ziggy O’Reilly +2 more
doaj +1 more source
Sally and… Cozmo? Training theory of mind using a toy robot: a pilot study
Frontiers in PsychologyIntroductionChildren with autism spectrum disorder (ASD) often show impairments in Theory of Mind (ToM). This pilot study examined whether a commercially available toy robot (Cozmo) could support false-belief training within an Applied Behavior Analysis (
Davide Ghiglino +4 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Right Temporoparietal Junction Involvement in Autonomic Responses to the Suffering of Others: A Preliminary Transcranial Magnetic Stimulation Study. [PDF]
, 2020 Functional neuroimaging studies have emphasized distinct networks for social cognition and affective aspects of empathy. However, studies have not considered whether substrates of social cognition, such as the right temporoparietal junction (TPJ), play a
Hastings, Paul D +2 more
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Selection pressure and organizational cognition: implications for the social determinants of health [PDF]
, 2001 We model the effects of Schumperterian 'selecton pressures' -- in particular Apartheid and the neoliberal 'market economy' -- on organizational cognition in minority communities, given the special role of culture in human biology.
Wallace, Rodrick
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source