Results 71 to 80 of about 1,226,113 (317)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Document Communication as a Form of Social Communication

Vestnik Volgogradskogo gosudarstvennogo universiteta. Serija 2. Jazykoznanije, 2014
The article considers the notion of document communication in its relation to the notions of communication and social communication. The author analyses the approaches to the classification of communication types, to identification of its components – subjects, object, channel, etc.
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Social-psychological influences on opinion expression in face-to-face and computer-mediated communication

, 2008
This study used an experiment embedded within a Web-based survey to examine the influence of contextual (i.e., face-to-face vs. online chat room discussion) and social-psychological factors on individuals' willingness to express opinions.
McLeod, Douglas M., Ho, Shirley S.
core   +1 more source

Community-Aware Social Community Recommendation

Proceedings of the 34th ACM International Conference on Information and Knowledge Management
Social recommendation, which seeks to leverage social ties among users to alleviate the sparsity issue of user-item interactions, has emerged as a popular technique for elevating personalized services in recommender systems. Despite being effective, existing social recommendation models are mainly devised for recommending regular items such as blogs ...
Runhao Jiang, Renchi Yang, Wenqing Lin
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

OrganiZational communication and organiSational communication: Binaries and the fragments of a field

, 2009
In this paper, I employ personal narrative to help cast light on connections and tensions between organiZational communication research, as produced in the United States, and organiSational communication research, as produced in Aotearoa New Zealand.
Ganesh, Shiv
core  

The Construction of Spectacular Religious-Political Rituals in Iran; A Critical Study [PDF]

Cyberspace Studies
Background: Following the Islamic Revolution and the expansion of access to visual media, the use of this media in Shia rituals, such as religious gatherings (hey’ats), significantly increased.
Ali Momeni, Abdollah Bicharanlou
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Intercultural Changes in Music Tastes of Iranian Adult Population: The Role of New Technologies, Media Convergence, and Globalization [PDF]

Cyberspace Studies
Music consumption, as an important form of cultural consumption in the daily lives of Iranians, has been the subject of political focus before and after the Revolution, 1979.
Abdollah Bicharanlou, Razieh Yasini, Farzad Gholami   +2 more
doaj   +1 more source