Results 131 to 140 of about 1,201,357 (310)

Social mobility in Australia project, 1973

open access: yes, 2007
3 major objectives. ( 1 ): To replicate the 1965 base line study of Australian stratification and mobility SSDA study nr.7. ( 2 ): To get more insight into social mobility and social stratification in Australia beyond the fairly restricted findings of ...
Broom, L., Duncan-Jones, P., Lancaster Jones, F. (primary investigator)
core   +1 more source

PHENOMENOLOGY OF DIGITAL LONELINESS IN WAR CONDITIONS: BETWEEN ALGORITHMIC HYPERPRESENCE AND EXISTENTIAL ISOLATION

open access: yesОсвітній дискурс
Relevance of the research. The article provides a phenomenological analysis of digital loneliness as a specific form of experiencing isolation in the conditions of algorithmic hyper-presence and military reality.
Serhii Terepyshchyi
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Peer Comparison for Improving Senior High School Students’ Achievement Motivation

open access: yesTazkiya Journal of Psychology
The desire for achievement creates motivation within the individual, where achievement motivation comes because of the need for achievement, which includes the desire to achieve success, complete difficult tasks, face challenges, and the desire to exceed
Salsabilla Arshalina Azzahra   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Enhancing satisfaction through downward comparison: the role of relational discontent and individual differences in social comparison orientation

open access: yes, 2001
Three experiments examined whether downward social comparison may enhance satisfaction in close relationships. In a thoughtgenerating task participants were asked to generate features of their relationship in which they considered their relationship as ...
de Dreu, CKW; id_orcid   +6 more
core   +1 more source

From support to pressure: the multiple associated effects of differential leadership patterns on the workplace behavior of university teachers in western China

open access: yesFrontiers in Psychology
IntroductionAlthough differential leadership is prevalent in Chinese organizations, its multiple effects on the workplace well-being and behavior of university teachers remain under-explored.
Junfeng Si   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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