Results 141 to 150 of about 1,206,427 (310)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Social preferences and social comparisons [PDF]
Chapter 1 introduces the thesis providing an overview of the common themes and methods underlying this research. Chapter 2 reports an experiment that examines the characteristics of effective leaders in a leader-follower voluntary contributions game. We focus on two factors: leaders’ cooperativeness and their beliefs about followers’cooperativeness. We
openaire +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Well-being comparisons and mental health outcomes following loss: a two-wave longitudinal study
Background: The loss of a significant other may lead to prolonged grief disorder (PGD), posttraumatic stress disorder (PTSD), depression, anxiety, somatic symptoms, and loneliness. Comparative thinking about one’s well-being (e.g.
Pascal Schlechter +3 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Replication Data for: Inequality in the Social Mind: Social Comparison and Support for Redistribution [PDF]
Replication files for "Inequality in the Social Mind: Social Comparison and Support for ...
Wichowsky, Amber, Condon, Meghan
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
SOCIAL COMPARISON AND SUBJECTIVE WELL-BEING: DOES THE HEALTH OF OTHERS MATTER? [PDF]
The importance of social comparison in shaping individual utility has been widely documented by subjective well-being literature. So far, income has been the main dimension considered in social comparison.
Vincenzo Carrieri
core
The relationship between social comparison orientations and self-consciousness [PDF]
departmental bulletin ...
鈴木, 公啓 +2 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

