Results 41 to 50 of about 253,410 (304)

The role of social and emotional competence on risk behaviors in adolescence [PDF]

open access: yes, 2012
The purpose of this study was to investigate the relation between social and emotional competence and substance use in adolescence, including tobacco, alcohol and illicit drugs.
Gaspar Matos, Margarida   +10 more
core  

Learning on work placement: The narrative development of social competence

open access: yes, 2009
This paper explores the development of social competence by examining examples of research interviews conducted with 35 British undergraduate students on work placements. Work placement schemes are a characteristic of contemporary higher education, which
Sims, D.   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Role of the Social Licence to Operate in the Emerging Bioeconomy—A Case Study of Short-Rotation Coppice Poplar in Slovakia

open access: yesLand, 2022
Wood plays a key role in the endeavours of the EU to establish a circular bioeconomy based on renewable biological resources. Today, forestry on its own cannot sustainably satisfy the demand for woody biomass.
Christine Pichler   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Development and Validation of the Social Emotional Competence Questionnaire (SECQ) [PDF]

open access: yes, 2012
Reliable and valid measures of children's and adolescents' social emotional competence (SEC) are necessary to develop in order to assess their social emotional development and provide appropriate intervention in child and adolescent development.
Jessie Ee   +3 more
core  

Digital learning in nursing education: lessons from the COVID-19 lockdown

open access: yesBMC Nursing
Background The COVID-19 pandemic necessitated a swift transition to e-learning, significantly impacting nursing education due to its reliance on practical, hands-on experiences and the critical role nurses play in healthcare.
Gro Gade Haanes   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

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