Results 51 to 60 of about 12,673,428 (296)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Pielęgniarstwo XXI Wieku, 2019 SELECTED SOCIO-DEMOGRAPHIC AND WORK-RELATED DETERMINANTS OF THE SOCIAL COMPETENCE OF PROFESSIONALLY ACTIVE NURSES Introduction. Social competence is a soft skill that allows, among other things, for better communication with the patient, establishing ...
Agnieszka Chrzan-Rodak +6 more
doaj +1 more source
Social Competence and Executive Functioning in Adolescents Following a Mild Traumatic Brain Injury [PDF]
, 2014 A traumatic brain injury (TBI) is one of the most common injuries sustained by adolescents and a leading cause of death and long-term disability. The vast majority of these cases are mild and yet they can cause a range of difficulties across multiple ...
Hollands, David Michael
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Learning on work placement: The narrative development of social competence
, 2009 This paper explores the development of social competence by examining examples of research interviews conducted with 35 British undergraduate students on work placements. Work placement schemes are a characteristic of contemporary higher education, which
Sims, D. +3 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Frontiers in PsychologyChildren’s decision-making is a socio-cognitive skill embedded within a broader system that promotes understanding of others and effective management of interpersonal contexts, making it closely linked to Theory of Mind (ToM) and empathy.
Elisabetta Lombardi +5 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
A rasch-based validity study of the HSCL-25
Journal of Affective Disorders Reports, 2021 Background: The Hopkins Symptom Checklist-25 (HSCL-25) is a commonly used questionnaire to assess anxiety and depression in trauma-affected refugees. Despite numerous studies evaluating criterion validity and reliability, few studies have assessed the ...
Erik Vindbjerg +4 more
doaj +1 more source