Results 71 to 80 of about 253,410 (304)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Fear Goliath or David? Inferring competence from demeanor across cultures

open access: yes, 2019
We examined cultural differences in people's lay theories of demeanor-how demeanor may be perceived as a straightforward and reliable reflection of reality (convergence theory) or as a deviating reflection of reality (divergence theory). Across different
Li, Ye   +3 more
core   +1 more source

The ecology of young children’s behaviour and social competence : child characteristics, socio-economic factors and parenting [PDF]

open access: yes, 2011
Using a longitudinal, UK representative sample from the Millennium Cohort Study, the present study examined the effects of socio-economic factors on mother- and teacher-rated behaviour, and the unique and cumulative contribution of both risk and ...
Dimitra Hartas, Hartas, Dimitra
core   +1 more source

FORMATION OF SOCIAL COMPETENCE OF FUTURE TEACHERS [PDF]

open access: yesVestnik Issyk-Kulʹskogo universiteta
Social competence is the ability of a person to effectively solve problems (both personal and social) in the process of interaction with society. In the information society and globalization, social competence of teachers is one of the key elements of ...
Sagimbekova D. S., Ordobaeva S. R.
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

KOMPETENSI SOSIAL GURU DALAM PEMBELAJARAN DAN PENGEMBANGANNYA

open access: yesTa'dib, 2012
Social competence of teachers is very supportive in the teaching and learning processes, both in the classroom and outside the classroom. One of the competences is social competence.
Hasbi Ashsiddiqi
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Extracurricular Activities And The Development Of Social Skills In Children With Intellectual And Learning Disabilities

open access: yes, 2013
Numerous skill deficits interfere with the social functioning of children with intellectual (ID) and learning disabilities (LD). Due to the limited effectiveness of social skill interventions for this population, it is necessary to explore additional ...
Brooks, Bianca A
core   +1 more source

The Development of Social Competence in Children with Disabilities

open access: yes, 2022
Children with disabilities experience unique challenges in developing social skills critical to achieve their social goals. In this chapter, the authors first introduce two theoretical frameworks that can guide research and practice relevant to social ...
Meyer, L. E.   +7 more
core   +1 more source

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