Results 71 to 80 of about 1,397,394 (301)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Health-Saving Competence of Future Primary School Teachers: Indicators of Development [PDF]
, 2020 The research revealed an increasing interest of scientists to the problem of formation of health-saving competence of future primary school teachers. This tendency is due to the need for a social inquiry to modernize the training of future educators ...
Бондаренко, Геннадій Леонідович +5 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
SOCIAL COMPETENCE DEVELOPMENT IN HIGH SCHOOL STUDENTS› SOCIALIZATION PROCESS
Sovremennye Issledovaniâ Socialʹnyh Problem, 2016 The article reveals the most important methodological problem aspects of students’ social competence definition in higher education socialization process.
Anzhelika Ahmetovna Novikova
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Children Involved in Child Protection: Hostile Attitudes as a Form of Agency
Social SciencesIntroduction: It is widely acknowledged that good quality relationships between social workers and children are essential to children’s non-formal inclusion in child protection processes.
Silvia Fargion, Diletta Mauri
doaj +1 more source
FORMATION OF SOCIAL COMPETENCE OF FUTURE TEACHERS [PDF]
Vestnik Issyk-Kulʹskogo universitetaSocial competence is the ability of a person to effectively solve problems (both personal and social) in the process of interaction with society. In the information society and globalization, social competence of teachers is one of the key elements of ...
Sagimbekova D. S., Ordobaeva S. R.
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
KOMPETENSI SOSIAL GURU DALAM PEMBELAJARAN DAN PENGEMBANGANNYA
Ta'dib, 2012 Social competence of teachers is very supportive in the teaching and learning processes, both in the classroom and outside the classroom. One of the competences is social competence.
Hasbi Ashsiddiqi
doaj +1 more source