Results 151 to 160 of about 2,297,329 (297)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Predictions of War Duration

open access: yesStats
The durations of wars fought between 1480 and 1941 A.D. were found to be well represented by random numbers chosen from a single-event Poisson distribution with a half-life of (1.25 ± 0.1) years. This result complements the work of L.F.
Glenn McRae
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Paying for Medical and Social Complexity in Massachusetts Medicaid.

open access: yesJAMA Netw Open, 2023
Alcusky MJ   +6 more
europepmc   +1 more source

The Morphospace of Consciousness

open access: yes, 2017
We construct a complexity-based morphospace to study systems-level properties of conscious & intelligent systems. The axes of this space label 3 complexity types: autonomous, cognitive & social.
Arsiwalla, Xerxes D.   +5 more
core  

COMPLEX CONTAGION IN SOCIAL SYSTEMS WITH DISTRUST

open access: yesAdvances in Complex Systems
Social systems are characterized by the presence of group interactions and by the existence of both trust and distrust relations. Although there is a wide literature on signed social networks, where positive signs associated to the links indicate trust, friendship, agreement, while negative signs represent distrust, antagonism, and disagreement, very ...
Jean-François de Kemmeter   +4 more
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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