Results 131 to 140 of about 2,297,329 (297)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Links Between Variation in Movement-Based Visual Signals and Social Communication Complexity in an Asian Agamid Lizard Phrynocephalus vlangalii

Animals
The social complexity hypothesis suggests that complex social interactions drive the evolution of sophisticated communicative signals. While the relationship between social communication and the complexity of sound and color signals has been extensively ...
Jian Liu, Qiaohan Hu, Yin Qi
doaj   +1 more source

Disentangling the evolutionary drivers of social complexity: A comprehensive test of hypotheses. [PDF]

Sci Adv, 2022
Turchin P, Whitehouse H, Gavrilets S, Hoyer D, François P, Bennett JS, Feeney KC, Peregrine P, Feinman G, Korotayev A, Kradin N, Levine J, Reddish J, Cioni E, Wacziarg R, Mendel-Gleason G, Benam M.   +16 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

FUEGOS SAGRADOS: EL TALLER METALÚRGICO DEL SITIO 15 DE RINCÓN CHICO (CATAMARCA, ARGENTINA) SACRED FIRES: THE METALLURGICAL WORKSHOP OF SITE 15 AT RINCÓN CHICO (CATAMARCA, ARGENTINA)

Boletín del Museo Chileno de Arte Precolombino, 2010
Numerosos estudios de laboratorio realizados sobre objetos de metal andinos aportaron valiosos datos sobre las características asumidas por la tecnología y el entramado simbólico en el cual se desarrollaron.
Luis R González
doaj  

Olfaction in (Social) Context: The Role of Social Complexity in Trajectories of Older Adults' Olfactory Abilities. [PDF]

J Aging Health, 2023
Goldman AW.
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

New evidence for regional pastoral practice and social complexity in the Eastern Tianshan Mountains in the first millennium BCE. [PDF]

Sci Rep, 2023
Wang Y, Monteith F, Xi T, Ren M, Li D, Hu S, Wang J, Festa M, Ma J.   +8 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Multi-isotope variation reveals social complexity in Viking Age Norway. [PDF]

iScience, 2022
Strand LM, Leggett S, Skar B.
europepmc   +1 more source