Results 211 to 220 of about 19,192,322 (351)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Social conditions facilitate water conservation in a solitary bee. [PDF]

J Insect Sci
Ostwald MM, Venegas VA, Seltmann KC.
europepmc   +1 more source

Higher prevalence of depressed mood in immigrants' offspring reflects their social conditions in the host country: The HELIUS study. [PDF]

PLoS One, 2020
Stronks K, Şekercan A, Snijder M, Lok A, Verhoeff AP, Kunst AE, Galenkamp H.   +6 more
europepmc   +1 more source

Epistemic Conditions and Social Preferences in Trust Games

It is well-known that subjects in bilateral bargaining experiments often exhibit choice behavior suggesting there are strong reciprocators in the population.
Gillies, Anthony S, Rigdon, Mary L
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Pobreza e HIV/AIDS: aspectos antropológicos e sociológicos

Cadernos de Saúde Pública
A partir da perspectiva das várias epidemias de HIV/AIDS que coexistem em mesmo espaço, bem como dos dados epidemiológicos do Brasil, acredita-se serem observáveis as variações já descritas alhures - feminilização, pauperização, juvenilização e ...
Richard Parker, Kenneth Rochel de Camargo Jr.   +1 more
doaj  

Mechanistic modeling of social conditions in disease-prediction simulations via copulas and probabilistic graphical models: HIV case study. [PDF]

Health Care Manag Sci
Khosheghbal A, Haas PJ, Gopalappa C.
europepmc   +1 more source

Social conditions for human happiness: A review of research.

International Journal of Psychology, 2015
R. Veenhoven
semanticscholar   +1 more source

Social policy and research environment in Zambia

, 1998
This paper has discussed a number of issues on the nature and state of social policy practice and research in Zambia. One interesting observation is that there is no specific conception of social policy in Zambia, but rather conceived in terms of ...
Chisanga, B., Masiye, G., Tembo, Robert, Mwanza, A.   +3 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source