Results 71 to 80 of about 6,200,273 (303)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Communication Library Mechanisms for Children’s Social Integration [PDF]

open access: yes, 2019
The article deals with communicative mechanisms of social interaction between libraries and different population categories. In conditions of information society, crisis situations, and war conflicts libraries should not only be supported by society but ...
Bozhuk, L   +4 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Russian Residents of the Murghab Sovereign’s Estate as an Ethnic Minority of the Murghab Oasis

open access: yesЖурнал Фронтирных Исследований
The problem of the relationships of the Russian minority within the closed socio-economic systems on the periphery of the Russian Empire is of significant interest in the context of understanding its phenomenon.
Dmitry V. Vasilyev
doaj   +1 more source

Prevalencia y factores asociados a la pediculosis en niños de un jardín infantil de Bogotá

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2008
Introducción. La pediculosis es una de las infestaciones crónicas más importante en escolares en el mundo. Objetivo. Estimar la prevalencia y describir la estacionalidad de la pediculosis durante siete meses en un jardín infantil y explorar su asociación
Ligia Inés Moncada   +4 more
doaj   +1 more source

Media interventions and new social imaginaries [PDF]

open access: yes, 2013
Recent re-articulations of the “social imaginary" (Castoriadis 1987) have emerged due to the proliferation and dispersion of new technologies in everyday life. What effect can enacting imaginative narratives for the near future have on present conditions?
Devereaux, Emile
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Social Conditions and Health

open access: yesAmerican Journal of Public Health, 2009
An introduction to the journal is presented in which the editor discusses the interaction of social conditions and health, which she describes as the theme of the articles published within the issue.
openaire   +3 more sources

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