Results 81 to 90 of about 6,200,273 (303)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Childbearing and psycho-social work life conditions in Sweden 1991-2000 [PDF]
In Sweden, a dramatic fall in fertility coincided with recession and high unemployment during the 1990s. Recent research has shown that the precarious labor market has been one factor contributing to women postponing family formation.
Ström, Sara
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
OBJETIVO: Com base nos dados da Pesquisa Nacional por Amostra de Domicílios (PNAD, 2004), foram comparadas as diferenças na prevalência de insegurança moderada/grave em relação à segurança alimentar, e insegurança leve quanto à posse de bens de consumo e
Leticia Marin-Leon +3 more
doaj +1 more source
The responsibility of Spanish garment retailers for the social and working conditions in Northern Morocco [PDF]
CCC_1The_responsibility_of_Spanish_garment_retailers_for_the_social_and_working_conditions_in_Northern_Morocco.pdf: 83 downloads, before Oct.
Clean Clothes Campaign
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Power of Trails for Promoting Physical Activity in Communities [PDF]
Highlights findings about trail characteristics and social conditions that attract regular users, how they influence levels of physical activity among different populations, and what it takes to build new trails.
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Reading Social Criticism of Tuk Drama in Richard Schechner’s Ac Diagram Perspective [PDF]
The main problem of this research is social criticism in the drama written in New Order era which was in repressive, authoritarian, and corruptive social political conditions.
NUR, SAHID
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

