Results 71 to 80 of about 829,876 (315)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Exploring motivated reasoning in polarization over the unfolding 2023 judicial reform in Israel

open access: yesCommunications Psychology
This work explored polarization over Israel’s Judicial Reform, introduced in January 2023. We find that the reform divided people into pro- and anti-reform camps, which differed in characteristics such as institutional trust, patriotism, and national ...
Dora Simunovic   +2 more
doaj   +1 more source

Social engagement revealed by gaze following in third-party observers of simulated social conflict. [PDF]

open access: yesFront Psychol, 2022
Champ TM   +5 more
europepmc   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Local knowledge matters: understanding the decision-making processes of communities under climate change in Suriname

open access: yesFrontiers in Climate
IntroductionTraditionally, local communities have relied on practical observations accumulated over extended periods to inform their decision-making.
Gwendolyn Smith   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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