Results 141 to 150 of about 11,902,515 (281)

Inefficient education spending in public school districts: a case for consolidation [PDF]

This paper estimates scale economies for Arkansas school districts. Large economies of scale exist in teacher salary and supply costs, as well as total costs.
Marvin E. Dodson, III, Thomas A. Garrett
core  

Delayed academic consolidation and active aging in European academia: a collaborative autoethnography of migrant women. [PDF]

Front Sociol
Vancea M, Duran-Salvadó N, De Ormaechea-Otarola V, Quirós-Domínguez C.   +3 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The Economics of Land Consolidation in Family Farms of Moldova [PDF]

The paper investigates the current situation with fragmentation of family farms in Moldova and its effects on family well-being and farm productivity. A key hypothesis is that consolidation of agricultural land in Moldova has beneficial effects in terms ...
Racul, Anatol, Cimpoies, Dragos, Lerman, Zvi   +2 more
core  

Shared digital, social, and cognitive mechanisms in gambling and pseudo-investment schemes in Kazakhstan: a multi-source qualitative study. [PDF]

Front Psychol
Khamzina Z, Buribayev Y.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Dyscoordination of thalamic reticular spindles is associated with social memory deficits in mice and humans with autism spectrum disorder. [PDF]

Nat Commun
Cui D, Wang X, Ai R, Gao F, Sun H, Zhang Y, Lyu Y, Zhang Z, Li W, Qin Y, Guo Y, Liu Y, Zhao N, Wang J, Li S, Wu Y, Zhang S, Wang C, Wang F, Li Y.   +19 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Magnetic Intramedullary Lengthening Nails for Complex Lower Extremity Reconstruction: Functional Outcomes, Bone Healing, and Complications. [PDF]

J Clin Med
Ergün M, Güler F.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source