Results 161 to 170 of about 518,499 (284)
The role of lipid metabolism in neuronal senescence
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Acute Exercise-Induced Epinephrine Elevation Promotes Post-Learning Memory Consolidation: A Narrative Review of Mechanisms and Implementation Strategies. [PDF]
Zhang Y, Lin X, Li G, Wang S.
europepmc +1 more source
PSYCHOLOGICAL ASPECTS OF UNIVERSITIES’ SOCIAL CAPITAL CONSOLIDATION
V. A. Chiker +2 more
openaire +2 more sources
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Shifting the centre of gravity in the global evidence ecosystem for health: strengthening local leadership and decision-making for national and global impact. [PDF]
Kuchenmüller T +22 more
europepmc +1 more source
Aretological Consolidation of Social and Moral Life [PDF]
openaire +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Resting after learning or repeating the learned? [PDF]
Martini M +5 more
europepmc +1 more source

