Results 111 to 120 of about 309,699 (265)

The (Social) Construction of Information Security

open access: yesThe Information Society, 2011
While the philosophical foundations of information security have been unexamined, there is an implicit philosophy of what protection of information is. This philosophy is based on the notion of containment, taken from analogies with things that offer physical security (e.g., buildings, safes, fences).
openaire   +2 more sources

The social construction of corruption : theoretical reflections

open access: yes, 2012
The volume demonstrates the suitability of the theory of social constructivism in portraying and analyzing the diversity of the phenomenon of corruption.
Tänzler, Dirk   +3 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Reflections on the Social Construction of Citizenship

open access: yesRecerca: Revista de Pensament i Anàlisi
It is not uncommon to find liberal cosmopolitan theorists who equate the concepts of citizenship, gender (or sex), and race. What is surprising, however, is that this is often done without a deep analysis of the concepts involved.
Francisco Blanco Brotons
doaj   +1 more source

The political construction of social inclusion through Further Education policy (1997 – 2007) [PDF]

open access: yes, 2009
This thesis explores ‘social inclusion’ as a political construction of the New Labour government between 1997 and 2007. The process of construction is frequently situated within policy from the Further Education (FE) sector. A critical discourse analysis
Williams, J.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Social Protection of Rural Workers in the Construction Industry in Urban China [PDF]

open access: yes
The construction industry is important for Chinese rural to urban migrants. Over 90% of urban construction workers are rural migrants, and over a third of all rural migrants work in construction.
Bingqin Li, Huamin Peng
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Précis: Categories We Live By

open access: yesJournal of Social Ontology, 2022
The project of Categories We Live By is to offer a metaphysics of social categories. The strategy is to give a theory of social properties of individuals.
Ásta
doaj  

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