Results 131 to 140 of about 3,278,528 (360)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

General systems perspective on achieving continuous synergy in a project organisation [PDF]

open access: yes, 2007
Studies of construction labour productivity have revealed that limited predictability and multi-agent social complexity make long-range planning of construction projects extremely inaccurate.
Radosavljevic, Milan
core  

The (Social) Construction of Information Security

open access: yesThe Information Society, 2011
While the philosophical foundations of information security have been unexamined, there is an implicit philosophy of what protection of information is. This philosophy is based on the notion of containment, taken from analogies with things that offer physical security (e.g., buildings, safes, fences).
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Social Construction and Education Values Based on the Study on Sangiran Museum

open access: yesHumaniora
The research analyzed the social indicators of history study and education values based on the Sangiran Museum study. Social and educational studies based on museum materials are still developing because they have potential prospects. Sangiran Museum is
Agung Budi Kurniawan
doaj   +1 more source

Formation Of Socio-economic Development Strategy Of Construction Enterprises [PDF]

open access: yes, 2018
The improvement of economic and social results of the current activity of a construction enterprise and future development of the socio-economic system is possible by forming and accepting complex arrangements within the mechanism of rationalization of ...
Bozhanova, V. (Viktoriia)   +1 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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