Results 141 to 150 of about 3,216,649 (304)

Division of childcare policy actors under health-oriented goals: thematic analysis of China’s policy texts from the social constructionist perspective

Frontiers in Public Health
BackgroundEnsuring child health, as a key objective of global childcare policies, requires coordinated efforts between the government, social organizations and communities, institutions, and families.
Linan Li, Junyu Li
doaj   +1 more source

The social construction of genomics and genetic analysis in ocular diseases in Ibadan, South-western Nigeria. [PDF]

PLoS One, 2022
Olawoye O, Salami KK, Azeez A, Adebola P, Sarimiye T, Imaledo J, Realini T, Hauser MA, Ashaye A.   +8 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The Social Construction of Stigma in Aged-Care Work: Implications for Health Professionals' Work Intentions. [PDF]

Gerontologist, 2022
Manchha AV, Way KA, Tann K, Thai M.
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Identity Selection and the Social Construction of Birthdays. [PDF]

Front Psychol, 2021
Pelham BW, DeHart T, Shimizu M, Hardin CD, Han HA, von Hippel W.   +5 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Diversity in Alzheimer's disease drug trials: Reflections on reporting and social construction of race. [PDF]

Alzheimers Dement, 2022
Babulal GM, Franzen S, Abner EL, Smith JE, van den Berg E, Mindt MR, van Bruchem-Visser RL, Schneider LS, Prins ND, Papma JM.   +9 more
europepmc   +1 more source

Urban public space and the construction of social life: a social-pedagogical perspective [PDF]

, 2012
Arendt H., Baacke D., Baum W.K., Biesta G., Boomkens R., Bourdieu P., Bouw C., Burke C., Chawla L., Corsaro W.A., Coussée F., Coussée F., De Visscher S., De Visscher S., De Visscher S., De Winter M., Delanty G., Gehl J., Giesecke H., Griet Verschelden, Hiemstra R., Hogan D., Howard E., Hämäläinen J., James A., Kampmann J., Katz C., Lepofsky J., Low S., Lynch K., Lynch K., Mantell W., Maria Bouverne-De Bie, Massey D., Matthews H., McKendrick J., Mitchell D., Nic Gabhainn S., Pink W.T., Portelli A., Prosser J., Rasmussen K., Rasmussen K., Raymund J.F., Schugurensky D., Sennett R., Sven De Visscher, Thompson P., Wildemeersch D., Wridt P.J.   +49 more
core   +1 more source

On Holiday! Policy and provision for disabled children and their families [PDF]

, 2007
This summary describes some findings from the On Holiday! study, carried out by the Thomas Coram Research Unit between 2004 and 2006 and funded by DfES.
Knight, A, Petrie, Pat, Potts, P, Zuurmond, M   +3 more
core   +1 more source