Results 31 to 40 of about 12,577,905 (258)
Social contract theory argues that to properly execute thematic versions of the selection task one has to specify, in the rules of such versions, an explicit benefit that can only be achieved in exchange for meeting a requirement.
Miguel López Astorga
doaj +1 more source
Background Effective supply chains for health products require an adequate, skilled workforce for supply chain management (SCM). Rwanda faces challenges in human resources for SCM, including limited capacity for SCM at different levels.
Erin Meier +5 more
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Neutrality and the Social Contract
Given the fact of moral disagreement, theories of state neutrality which rely on moral premises will have limited application, in that they will fail to motivate anyone who rejects the moral premises on which they are based.
Ian J. Carroll
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Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Redrawing state-society boundaries: Egypt's dynamic social contract [PDF]
Most LDC regimes, especially those with a colonial past, suffer from a deficit in legitimacy. Basing their rule on the personality and achievements of one person, these regimes have failed to pass on their legitimacy to their successors, or sometimes ...
Kamel, Maggie Samir, Kamel, M.S.
core
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
This contribution aims to use social history and social theory to investigate political power and compliance with authority in ancient Western Asia, through the case study of Neo-Assyrian imperial building projects.
Marta Lorenzon, Caroline Wallis
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Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source

