Results 41 to 50 of about 110,478 (260)

A Social Contract for Home Education: A Framework for the Homeschooling Debate

open access: yesEncyclopaideia, 2023
Elective home education has become an international trend characterized by considerable public controversy and much legal fragmentation. Issues related to whether it should be permitted and how it should be monitored are currently being debated in many ...
Anna Chinazzi
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Theoretical sources of the social state

open access: yesУкраїнський соціум, 2023
The growing demand of the Ukrainian society to “reboot” the state actualizes the rethinking of the sources and content of the theory of the social state for the scientific justification of the post-war recovery, transformation of the economy and the ...
Nebrat V. V.
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Study on status quo of psychological contract of nursing assistants and its influencing factors

open access: yesHuli yanjiu, 2021
ObjectiveTo explore the study on status quo of psychological contract of nursing assistants and its influencing factors.MethodsThe general information questionnaire and the Psychological Contract Scale were used to survey 423 nursing assistants employed ...
WANG Jing   +4 more
doaj  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

From the Social Contract to a Social Contract Law - Vom Contrat Social zum Gesellschaftsvertragsrecht

open access: yesAncilla Iuris, 2008
Taking the viewpoint of the civil law tradition, which has traditionally assumed that the legitimacy of the administration is state-derived, this text recognises the constant decline of state sovereignty in modern times and consequently the increasing ...
Andreas Abegg
doaj  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Neutrality and the social contract [PDF]

open access: yesLes Ateliers de l’Ethique, 2009
Given the fact of moral disagreement, theories of state neutrality which rely on moral premises will have limited application, in that they will fail to motivate anyone who rejects the moral premises on which they are based.
Ian J. Carroll
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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