Results 41 to 50 of about 12,204,790 (298)

Deontic logic and adaptive algorithms: The relevance of explicit benefit in versions of the selection task

open access: yesFilosofia Unisinos, 2013
Social contract theory argues that to properly execute thematic versions of the selection task one has to specify, in the rules of such versions, an explicit benefit that can only be achieved in exchange for meeting a requirement.
Miguel López Astorga
doaj   +1 more source

Invasion of Optimal Social Contracts

open access: yesGames, 2023
The stag-hunt game is a prototype for social contracts. Adopting a new and better social contract is usually challenging because the current one is already well established and stable due to sanctions imposed on non-conforming members. Thus, how does a population shift from the current social contract to a better one?
Alessandra F. Lütz   +3 more
openaire   +5 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Social Contract with Endogenous Sentiments [PDF]

open access: yesSSRN Electronic Journal, 2006
Moral values infuence individual behavior and social interactions. A specially signif- cant instance is the case of moral values concerning work e¤ort. Individuals determine what they take to be proper behaviour and judge the others, and themselves, accordingly.
Matteo Cervellati   +2 more
openaire   +5 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Building Walls, Social Groups and Empires: A Study of Political Power and Compliance in the Neo-Assyrian Period

open access: yesAsia Anteriore Antica, 2023
This contribution aims to use social history and social theory to investigate political power and compliance with authority in ancient Western Asia, through the case study of Neo-Assyrian imperial building projects.
Marta Lorenzon, Caroline Wallis
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

From the Social Contract to a Social Contract Law - Vom Contrat Social zum Gesellschaftsvertragsrecht

open access: yesAncilla Iuris, 2008
Taking the viewpoint of the civil law tradition, which has traditionally assumed that the legitimacy of the administration is state-derived, this text recognises the constant decline of state sovereignty in modern times and consequently the increasing ...
Andreas Abegg
doaj  

Study on status quo of psychological contract of nursing assistants and its influencing factors

open access: yesHuli yanjiu, 2021
ObjectiveTo explore the study on status quo of psychological contract of nursing assistants and its influencing factors.MethodsThe general information questionnaire and the Psychological Contract Scale were used to survey 423 nursing assistants employed ...
WANG Jing   +4 more
doaj  

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