Results 11 to 20 of about 2,412,568 (265)

Choice in the context of informal care-giving [PDF]

, 2007
Extending choice and control for social care service users is a central feature of current English policies. However, these have comparatively little to say about choice in relation to the informal carers of relatives, friends or older people who are ...
Allen I., Appleby J., Arksey H., Audit Commission, Bell J., Cabinet Office, Carers National Association, Caring Costs Alliance, Clarke J., Commission for Social Care Inspection, Department for Work and Pensions, Department of Health, Department of Health, Department of Health, Dowding K., Ellis K., Giddens A., Hadley R., Hasler F., Hirsch C.H., Howard M., Joshi H., Kagan C., Klein R., Larkin J.P., Lent A., Levin E., Macgregor G., Mayo E., McLaughlin E., Minichiello V., Mooney A., Morris J., Morris J., Myers F., Needham C., Nolan M., Parker G., Parker G., Parry J., Penrod J., Pickard L., Pickard L., Princess Royal Trust for Carers, Qureshi H., Royal Commission on Long Term Care, Schwartz B., Scottish Executive, Scourfield P., Seddon D., Seddon D., Shakespeare T., Tilse C., Twigg J., Twigg J., Twigg J., Vernon A., Welsh Assembly Government   +57 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Informal Authority in the Workplace [PDF]

, 2010
{Excerpt} In most types of organizations, formal authority is located at the top as part of an exchange against fairly explicit expectations. In networked, pluralistic organizations that must rapidly formulate adaptive solutions in an increasingly ...
Serrat, Olivier
core   +1 more source

Nominal or Real? The Impact of Regional Price Levels on Satisfaction with Life [PDF]

, 2013
According to economic theory, real income, i.e., nominal income adjusted for purchasing power, should be the relevant source of life satisfaction. Previous work, however, has only studied the impact of inflation adjusted nominal income and not taken into
A E Clark, A E Clark, A Ferrer-I Carbonell, A Ferrer-I-Carbonell, A Finkelstein, A Oswald, A Oswald, A Stutzer, A Stutzer, Armin Falk, B S Frey, B Weber, C Senik, D Kahneman, Di Tella, E Fehr, E Shafir, Efp Luttmer, G Akerlof, G G Wagner, Hannah Schildberg-Hörisch, I Fisher, J Schupp, J Stiglitz, K Fliessbach, M M Grabka, P Dolan, R Chetty, R Kawka, R Layard, S Boes, T Blumkin, Thomas Deckers   +32 more
core   +4 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Must Realists Be Pessimists About Democracy? Responding to Epistemic and Oligarchic Challenges [PDF]

, 2021
In this paper we show how a realistic normative democratic theory can work within the constraints set by the most pessimistic empirical results about voting behaviour and elite capture of the policy process.
Arlen, Gordon, Rossi, Enzo
core   +2 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Encounters between security guards and young people: the extent and biases of formal social control

Policing and Society, 2014
There is a distinct lack of knowledge about how the rise of private security relates to young people in adversarial encounters. Prior studies suggest that the policing of young people by police is a common occurrence and social biases exist. However, policing of young people by private security guards has gained much less attention.
Saarikkomäki, Elsa, Kivivuori, Janne
openaire   +4 more sources

Formal control influence on franchisee trust and brand-supportive behavior within franchise networks [PDF]

, 2019
Although management scholars recognize that intention of formalization influences the manner in which formal controls are applied within organizations, this issue has been largely overlooked in research on strategic alliances including franchise networks.
Owens, Martin, Sydow, Jörg, Yakimova, Raisa   +2 more
core   +2 more sources