Results 41 to 50 of about 475,478 (302)

Understanding consumers’ behavior intention of recycling mobile phone through formal channels in China: The effect of privacy concern

open access: yesResources, Environment and Sustainability, 2021
The aim of this paper is to explore consumers’ intention of recycling obsolete mobile phone through formal channels in China. Taking Jiangsu Province as an example, the survey results revealed that although nearly half of consumers prefer to save their ...
Ling Zhang   +4 more
doaj   +1 more source

Encounters between security guards and young people: the extent and biases of formal social control

open access: yesPolicing and Society, 2014
There is a distinct lack of knowledge about how the rise of private security relates to young people in adversarial encounters. Prior studies suggest that the policing of young people by police is a common occurrence and social biases exist. However, policing of young people by private security guards has gained much less attention.
Saarikkomäki Elsa, Kivivuori Janne
openaire   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Attributes Of Police Leadership

open access: yesRevista Criminalidad, 2019
The purpose of this article is to identify the attributes of police leadership and their relationships, associated with the dimensions of to be, to know, know-how, and know to be of the police officer. The methodological design used is of mixed type. For
Juan Carlos Nieto-Aldana   +2 more
doaj  

MOTIVATIONS, IMPORTANCE, CHALLENGES AND PERSPECTIVES OF SOCIAL CONTROL IN HEALTH

open access: yesCogitare Enfermagem, 2019
Purpose: To understand the motivations, importance, challenges and perspectives for acting as local health counselors in the Unified Health System.Method: A qualitative and descriptive study of the exploratory type conducted with 15 local health ...
Carlos Junglos   +3 more
doaj   +1 more source

Sociological concept of morale [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2012
The author first discusses the overall unity of the total normative regulation, from which it is separated in the late Roman empire the right, but only in the new century and the morale.
Marjanović Miloš
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Paying for Crimes and Earning Heaven. Daily Life of Imprisoned Women at “El Buen Pastor” Penitentiary 1890-1929.

open access: yesHistoria y Memoria, 2015
During the period of Colombian conservative hegemony, “El Buen Pastor” prison, in Bogotá, provides an illustration of penitentiary politics, as well as the formal and informal mechanisms of social control at the time, gathered in a single institution. In
July Andrea García Amézquita
doaj   +1 more source

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