Results 51 to 60 of about 2,768,666 (306)

Post-Socialist Anomie Through the Lens of Economic Modernization and the Formalization of Social Control [PDF]

open access: yesSSRN Electronic Journal, 2013
This paper inquires into how economic modernization impacts normative regulation by spurring, on the one hand (a) formal media of normative regulation (also known as formal social control) in the spheres of politics, economics and interpersonal relations and, on the other hand, (b) informality via the lower density of norms (also known as anomie). This
Christopher Swader, Leon Kosals
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Sociological concept of morale [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2012
The author first discusses the overall unity of the total normative regulation, from which it is separated in the late Roman empire the right, but only in the new century and the morale.
Marjanović Miloš
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

MOTIVATIONS, IMPORTANCE, CHALLENGES AND PERSPECTIVES OF SOCIAL CONTROL IN HEALTH

open access: yesCogitare Enfermagem, 2019
Purpose: To understand the motivations, importance, challenges and perspectives for acting as local health counselors in the Unified Health System.Method: A qualitative and descriptive study of the exploratory type conducted with 15 local health ...
Carlos Junglos   +3 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

An anarchist’s reflection on the political economy of everyday life [PDF]

open access: yes
James Scott has written a detailed ethnography on the lives of the peoples of upland Southeast Asia who choose to escape oppressive government by living at the edge of their civilization.
Boettke, Peter
core   +4 more sources

Attributes Of Police Leadership

open access: yesRevista Criminalidad, 2019
The purpose of this article is to identify the attributes of police leadership and their relationships, associated with the dimensions of to be, to know, know-how, and know to be of the police officer. The methodological design used is of mixed type. For
Juan Carlos Nieto-Aldana   +2 more
doaj  

Paying for Crimes and Earning Heaven. Daily Life of Imprisoned Women at “El Buen Pastor” Penitentiary 1890-1929.

open access: yesHistoria y Memoria, 2015
During the period of Colombian conservative hegemony, “El Buen Pastor” prison, in Bogotá, provides an illustration of penitentiary politics, as well as the formal and informal mechanisms of social control at the time, gathered in a single institution. In
July Andrea García Amézquita
doaj   +1 more source

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