Results 21 to 30 of about 434,699 (261)

Human-machine in the vortex of digital synergy

Humanities & Social Sciences Communications
This study explores whether experience with AI tools and the intensity of their use influence individuals’ adoption of ChatGPT in the Czech Republic. Using data from 1232 respondents (aged 15+), collected via a quota-based online survey from April 8 to ...
Vaclav Moravec, Beata Gavurova, Nik Hynek, Martin Rigelsky   +3 more
doaj   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Agencias socializadoras del control social formal en la prevención del delito contra la vida

Santiago, 2020
En los últimos años se ha experimentado en la provincia de Guantánamo un incremento de la comisión del delito contra la vida evidenciándose una mayor incidencia en las comunidades; escenario importante para el desarrollo histórico de nuestra nación, como
Lilian Lorente-Ocaña, Deneisi Rodríguez-Cardona   +1 more
doaj  

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

The need to standardize use of the newly deceased in medical trainings [PDF]

Clinics
OBJECTIVES: The present study aimed to identify the characteristics of use of the deceased in invasive training and the bioethical principles that govern this practice.
Fábio Roberto Cabar, Daniele Costa Rachid Lacerda, Gabriela Thomé Souza de Freitas, Maria Luiza Gorga   +3 more
doaj   +2 more sources

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Predictors of the prevalence and importance of the observed trinary control system in rural China

Humanities & Social Sciences Communications
Western criminological literature continues to focus on the binary control system (formal vs. informal), while China has long employed the trinary system (formal, semiformal, and informal) in its construction of social control.
Shanhe Jiang, Dawei Zhang, Darrell D. Irwin, Xin Jiang, Yichen Zhao   +4 more
doaj   +1 more source

El control social informal como estrategia para la promoción de la seguridad ciudadana y la prevención de los delitos en Ecuador

Revista Metropolitana de Ciencias Aplicadas
En esta investigación se analiza el control social informal como estrategia para la promoción de la seguridad ciudadana y la prevención de los delitos en el Ecuador, en atención a los distintitos tipos de control social informal y sus diferencias con el
Carlos Eduardo Durán-Chávez, Eugenio Égüez-Valdivieso   +1 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source