Results 81 to 90 of about 475,496 (302)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Niños que se portan mal : el control social formal sobre la infancia infractora inimputable [PDF]
, 2017 Memoria (licenciado en ciencias jurídicas y sociales)Nuestro trabajo de investigación tiene por objeto describir el efecto criminógeno que el control social formal posee sobre la población infractora inimputable desde una perspectiva criminológica ...
Wäckerling Avalos, Nicole Andrea
core
Contingent Control and Wild Moments: Conducting Psychiatric Evaluations in the Home
Social Inclusion, 2019 When social control and social service workers go into the field, into the “native habitat” of some problem, a variety of tacit structures and controls that mark office work with its standardized documents and formal meetings are weakened or absent ...
Robert M. Emerson, Melvin Pollner
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Fairness, justice, subjectivity, objectivity and goal congruence in management control systems [PDF]
Management control systems are intended to motivate managers to ensure that organizational goals are accomplished. They do this by rewarding and promoting people according to certain criteria.
Rosanas, Josep M., Cuguero, Natalia
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The social control–social capital debate about distance and online teacher education: critical reflections on two courses at the University of Southern Queensland, Australia [PDF]
, 2006 [Abstract]: One among several crucial conceptual lenses that should be deployed in interrogating the effectiveness of an open learning approach to teacher education is the social control–social capital debate.
Danaher, Patrick Alan
core
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2011 Introduction: Abortion has always been a controversial issue and all religions, humanistic and medical communities have opposed it . The complications of illegal abortion are one of the most common reasons of hospital admission in developing countries. W.
M Ghadipasha +5 more
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
El control formal, la criminología y los casos [PDF]
, 2002 Me propongo en este trabajo analizar la incidencia de la Criminología en un segmento importante del control social formal, a saber, los procesos de construcción y evaluación de los casos penales. También insinuar sus aportes posibles en la evaluación de
Domenech, Ernesto Eduardo
core +2 more sources
YoungResearch and political discourse primarily emphasize social control within minority families, overlooking a broader perspective concerning diverse agents and contexts.
Tina Bojovic +2 more
doaj +1 more source