Results 141 to 150 of about 1,601,951 (261)

Social Control of Hypothalamus-Mediated Male Aggression. [PDF]

Neuron
Yang T, Yang CF, Chizari MD, Maheswaranathan N, Burke KJ, Borius M, Inoue S, Chiang MC, Bender KJ, Ganguli S, Shah NM.   +10 more
europepmc   +1 more source

Depression, perceived social control, and hypothalamic-pituitary-adrenal axis function in African-American adults. [PDF]

Health Psychol, 2020
Obasi EM, Chen TA, Cavanagh L, Smith BK, Wilborn KA, McNeill LH, Reitzel LR.   +6 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Social control is associated with increased reproductive skew in a wild mammal. [PDF]

Biol Lett
Maldonado-Chaparro AA, Philson CS, Zhang X, Blumstein DT.   +3 more
europepmc   +1 more source

Broken Windows, Informal Social Control, and Crime: Assessing Causality in Empirical Studies. [PDF]

Annu Rev Criminol, 2020
Lanfear CC, Matsueda RL, Beach LR.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The Dynamics of Adolescent Relationships and the Disintegration of Moral Regulation

Jurnal Sosiologi Agama
Unplanned pregnancies among teenagers are often perceived merely as a lapse in individual self-discipline. Nevertheless, in Paremono Village, located in Magelang Regency, a community that upholds strong Islamic values, this issue reveals a sociological
Ria Nur Cahyani, Amika Wardana, Tomy Lovendo   +2 more
doaj  

Health-related social control in overweight romantic couples: daily associations with physical activity and affect for targets and agents. [PDF]

Ann Behav Med
Küng P, Berli C, Höhener PS, Tobias R, Scholz U.   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source