Results 121 to 130 of about 7,713,270 (293)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Health-Related Social Control and Perceived Stress Among High-Risk Latina Mothers with Type 2 Diabetes and Their At-Risk Adult Daughters. [PDF]

open access: yesInt J Behav Med, 2023
Cervantes-Ortega M   +9 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Benefícios compartilhados: um mecanismo para induzir a participação da sociedade no controle dos gastos públicos no Brasil

open access: yesEconomia Aplicada, 2004
The present paper analyses the incentives individual members of society face to contribute to a nation's corruption control effort. A decision-theoretic model shows that agents do have an interest to dedicate part of their resources to the nation's ...
Laércio Mendes Vieira   +2 more
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Le virtù del pettegolezzo

open access: yesStoria delle Donne, 2011
In this work a theory of gossip as a means for social control is proposed. Exercising social control roughly means to isolate and/or to punish cheaters.
Rosaria Conte
doaj  

Long-Term Antecedents and Outcomes of Perceived Control [PDF]

open access: yes
Perceived control plays an important role in shaping development throughout adulthood and old age. Using data from the adult lifespan sample of the national German Socio-Economic Panel (SOEP; N > 10,000, covering 25 years of measurement), we explored ...
Denis Gerstorf   +4 more
core  

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