Results 111 to 120 of about 20,375,884 (207)

The Impact of COVID-19 Pandemic Level 3 Alert on the Incidence of Anxiety and Mood Disorder in Taiwan: An Interrupted Time Series Analysis

open access: yesTaiwanese Journal of Psychiatry
Objective: In this study, we intended to evaluate the impact of Taiwan’s COVID-19 pandemic Level 3 alert on anxiety and mood disorders, focusing on age and gender differences. We hypothesized that individuals aged 43+ years, who experienced the 2003 SARS
Pei-Yi Cheng   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Estudio Longitudinal Social de Chile 2016-2021

open access: yes
ELSOC has been designed to evaluate how Chileans think, feel, and behave regarding a set of social issues related to conflict and social cohesion in Chile.
Reproducible Research, Centre for Social Conflict and Cohesion Studies COES
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Los Angeles County Social Survey, 1997 (LACSS)

open access: yes
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

La Educación Social como objeto de estudio de la Pedagogía Social [PDF]

open access: yes, 2011
La Pedagogía Social es una disciplina que integra los saberes y conocimientos especializados relacionados con la praxis de la Educación Social y que se desarrolla mediante competencias intelectuales y técnicas para intervenir en el amplio marco de la ...
Gallardo Vázquez, Pedro   +1 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Musée social.

open access: yes, 1896
Title from caption.Mode of access ...
Musée social (Paris, France)
core  

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