Results 101 to 110 of about 1,956,577 (310)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Social work practice in Zimbabwe [PDF]

open access: yes, 1991
The development of social work in Zimbabwe is closely tied to the country's colonial history, its orientation reflecting a wholesale transfer from the British experience. Social work in Zimbabwe developed as a response to urban social ills such as crime,
Kaseke, Edwin
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Theory of Social Control and the Social Psychology of Dissatisfaction: Inhibition, regression and isolation in a cultural context [PDF]

open access: yes, 2011
The Theory of Social Control (TSC) is grounded in satisfaction and happiness research. The study investigated the reasons behind relatively low levels of civil and personal satisfaction, subjective social well-being and experienced happiness in the post ...
Orsolya Selymes, PhD Candidate
core  

Dal protettore al controllore. Uno sguardo sociologico sulla letteratura disegnata a tema supereroistico

open access: yesIm@go. A Journal of the Social Imaginary, 2015
1938: a flying man with an S on his breast appears in the sky of an American metropolis, catapulting cartoon mass entertainment into a new dimension. 1986: a spot of blood on a Smiley icon (Moore, 1986) puts an end to the innocence of an entire narrative
Pier Paolo Zampieri
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Congresos criminológicos internacionales y su impacto en los códigos penales de América Latina (1870–1945)

open access: yesRechtsgeschichte - Legal History, 2022
Departing from the analysis of different international congresses concerning criminal issues carried out between 1870 and 1945 mostly in Europe, the article traces the expansion of the category of »dangerousness« (estado de peligrosidad) in Latin ...
Elizabeth Gómez Alcorta
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Defending Others Online: The Influence of Observing Formal and Informal Social Control on One's Willingness to Defend Cyberhate Victims. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Costello M   +7 more
europepmc   +1 more source

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