Results 81 to 90 of about 1,518,790 (262)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Dal protettore al controllore. Uno sguardo sociologico sulla letteratura disegnata a tema supereroistico

open access: yesIm@go. A Journal of the Social Imaginary, 2015
1938: a flying man with an S on his breast appears in the sky of an American metropolis, catapulting cartoon mass entertainment into a new dimension. 1986: a spot of blood on a Smiley icon (Moore, 1986) puts an end to the innocence of an entire narrative
Pier Paolo Zampieri
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Defending Others Online: The Influence of Observing Formal and Informal Social Control on One's Willingness to Defend Cyberhate Victims. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Costello M   +7 more
europepmc   +1 more source

The Impact of COVID-19 Pandemic Level 3 Alert on the Incidence of Anxiety and Mood Disorder in Taiwan: An Interrupted Time Series Analysis

open access: yesTaiwanese Journal of Psychiatry
Objective: In this study, we intended to evaluate the impact of Taiwan’s COVID-19 pandemic Level 3 alert on anxiety and mood disorders, focusing on age and gender differences. We hypothesized that individuals aged 43+ years, who experienced the 2003 SARS
Pei-Yi Cheng   +3 more
doaj   +1 more source

Policing the poor through space: The fil rouge from criminal cartography to geospatial predictive policing

open access: yesOñati Socio-Legal Series, 2022
Recent years have witnessed an explosion of interest in predictive policing, with a clear opposition emerging between supporters and critics of its implementation.
Carlo Gatti
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Disrupted computations of social control in individuals with obsessive-compulsive and misophonia symptoms. [PDF]

open access: yesiScience, 2022
Banker SM   +6 more
europepmc   +1 more source

Recensione / Recension / Book Review [PDF]

open access: yesRivista di Criminologia, Vittimologia e Sicurezza, 2011
Book review of: Bravo F., Criminalità economica e controllo sociale. Impresa etica e responsabilità ex d.lgs.
Vasaturo Giulio
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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