Results 91 to 100 of about 7,713,270 (293)
Revista de Administração Pública, 2013 Este trabalho analisa o exercício do controle social no Brasil, a partir do debate geral que o estimulou e do contexto interno que culminou na criação de espaços institucionalizados para sua aplicação. Tem-se como objetivo avaliar o exercício do controle
Claudio Gurgel, Agatha Justen
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Social Security Reform with Self-Control Preferences [PDF]
This paper analyzes a fully funded social security system under the assumption that agents face temptation issues. Agents are required to save through individually managed Personal Security Accounts without, and with mandatory annuitization.
Athanasios C. Thanopoulos +1 more
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Psychosocial resources and social health inequalities in France: Exploratory findings from a general population survey [PDF]
We study the psychosocial determinants of self-assessed health in order to explain social inequalities in health in France. We use a unique general population survey to assess the respective impact on self-assessed health status of subjective perceptions
Florence Jusot +2 more
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Rechtsgeschichte - Legal History, 2022 Departing from the analysis of different international congresses concerning criminal issues carried out between 1870 and 1945 mostly in Europe, the article traces the expansion of the category of »dangerousness« (estado de peligrosidad) in Latin ...
Elizabeth Gómez Alcorta
doaj
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
El despliegue del paternalismo industrial en la Compañía Minera e Industrial de Chile (1920-1940)
Historia Crítica, 2015 Within the framework of industrial paternalism this article analyzes the strategies of “extensive” control applied by the coal-mining industries in the district of Lota-Coronel in southern Chile.
Hernán Venegas Valdebenito +1 more
doaj +1 more source