Results 51 to 60 of about 323,543 (240)
, 2011 The Social Control of the activities of public administration, have been essential to ensure that their managers are responsive and provide for their decisions to pursue the public interest. The traditional mechanisms of control, well established among the three powers, have proved insufficient in the face of the multiplicities of the demands of ...
Vieira, Evaneide Dutra +1 more
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Moral responsibility of government employees
Aspekti Publìčnogo Upravlìnnâ, 2015 The paper dwells on the issue of re-conceptualization and revaluation of the moral responsibility of public servants in the current context of public administration in Ukraine.
V. F. Zolotarov, S. I. Bilosorochka
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Educação: Teoria e Prática, 2009 This article presents the main elements of the Brazilian State reform project, expressed in the document known as the Guiding Plan for the Reform of the State Apparatus (1995), in which reference is mainly to the alterations in the public administration
Regina Tereza Cestari de Oliveira +1 more
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AI implementation as the key element for public administration modernization [PDF]
Zbornik Radova: Pravni Fakultet u Novom SaduIn modern society, public administration is divided into central government administration, local government units and public services established to fulfill various public needs of community users.
Klarić Mirko Z., Boban Josip Lucijan Z.
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Field of Social Regulation: How the State Creates a Profession
Professions and Professionalism, 2013 This article describes the process of professionalisation in the field of social control in Sweden. The aim is to analyse how the state by legislation created the profession of social workers for local social services and thus for social control by ...
Kerstin Svensson, Karsten Åström
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