Results 51 to 60 of about 182,811,015 (279)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Applying design in public administration: a literature review to explore the state of the art [PDF]
, 2019 The attention for applying design-oriented approaches in public administration has increased significantly. Applying design is seen as a promising way to deal with wicked problems and create more responsive policies and services.
Hermus, Margot +2 more
core +1 more source
THE DOCTRINE OF POLITICAL CORRECTNESS AND ITS ROLE IN THE PUBLIC ADMINISTRATION OF MODERN SOCIETY
Публічне управління та регіональний розвитокThe article analyzes the doctrine of political correctness and its role in the public administration of modern society. It is established that the doctrine of political correctness involves the direct or indirect prohibition of disclosing certain ...
Nataliya Yevtushenko
doaj +1 more source
SOME FEATURES OF THE NEW PUBLIC MANAGEMENT [PDF]
Challenges of the Knowledge Society, 2021 The profound changes experienced by the public administration in the last twenty years, which are closely correlated with the economic and social phenomena, were based on the particularities of the New Public Management, an event of great significance ...
Florina POPA
doaj
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Ecological IndicatorsAccurately identifying ecosystem-service (ES) responses to future climate change is essential for improving ecological conservation and restoration and for developing targeted adaptation strategies. However, coherent future response zones across multiple
Xiaosong Tu +10 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Theoretical basis of comparison of models of public administration [PDF]
, 2013 In connection to the process of the public administration reforms which take place in most of the European countries and also in connection to the "European administrative space", the issues of studying and mutually comparing administrative systems of ...
Čechák, Vladimír
core +1 more source
İslâm’da İdâre’nin (Kâmû Velâyeti ve Vilâyeti’nin) Denetimi
İslami İlimler Dergisi, 2018 Özİdâre, İslâm Toplumu’nda dînin bir rüknü sayılmış, varlığı ile İslâm’ın varolacağı, yokluğu ile İslâm’ın sözkonusu olamayacağı vurgulanmıştır. Toplumdüzenini sağlamayı amaçlayan İslâm Hukuku, toplum düzenin ayaktatutan İdâre’yi de tanzîmetmiştir ...
Mehmet Nuri Güler
doaj